PHS 615 - Pharmacogenomics and Pharmacogenetics

The course is designed to provide students with a broad overview of the importance and application of patient-specific genetic information to individualization of pharmacotherapy. Content includes a review of essential principles of genetics, and the effect of genetic variation on the pharmacokinetic and pharmacodynamic response of various medications. The ethical and legal implications that arise due to genetic testing will also be discussed. The mechanisms whereby pharmaceuticals alter gene expression will also be examined. Finally, the principles of gene therapy and protein pharmaceuticals will be presented. (Offered as needed.) 2 credits